Innovating Therapeutic Discovery Together

At PolyPhase, we are reimagining the future of drug discovery. Our platform utilizes ultra-throughput, disease-agnostic screening to test multiple disease models simultaneously, providing unparalleled insight into potential drug candidates.

Our Cutting-Edge Technology

Utilizing our proprietary imaging platform, we enable high-speed, multi-model testing, reducing the time and cost associated with traditional drug development methods.

Our approach is designed to prioritize polypharmacological compounds that interact with multiple biological targets, expanding the range of therapeutic possibilities.

Innovative Therapeutic Discovery

Targeting biomolecular condensates for unprecedented small molecule discovery in neurological disorders & other condensatopathies

UltraMAC Cell Profiling

What sets PolyPhase apart is our ability to prioritize polypharmacological drugs—those capable of interacting with multiple biological pathways.

Patients deserve better

These compounds offer a new frontier in medicine, where the focus shifts from single-target drugs to treatments that address the complexity of diseases through multi-target mechanisms.

Saving time and money

From neurodegenerative conditions to cancer, infectious diseases, and beyond, single target studies are expensive often leading to poor outcomes

The UltraMAC Platform

Ultra-Throughput Modulation of Aberrant Condensates

Our platform not only offers speed and scalability, but also unparalleled precision in identifying the most promising therapeutic leads

Ultra-Throughput Profiling

Our system allows mapping >7,000 therapeutics- condensate interactions per 384-well plate.

Multicolor Imaging

Illuminating differential but interconnected condensate dynamics across diseases

Computational Deconvolution

By leveraging powerful computational algorithms and analytics, we can efficiently process terabytes of data.

Dynamic Assemblies

Optimizing the drug discovery process and uncovering novel candidates that would otherwise be missed.

Connect with PolyPhase

Reach out to explore therapeutic discovery and condensate profiling.